Here, the glucose ring is phosphorylated. The enzyme that catalyzes this reaction is hexokinase. The first step in glycolysis is the conversion of D-glucose into glucose-6-phosphate. The overall reaction of glycolysis which occurs in the cytoplasm is represented simply as:Ĭ 6H 12O 6 + 2 NAD + + 2 ADP + 2 P -–> 2 pyruvic acid, (CH 3(C=O)COOH + 2 ATP + 2 NADH + 2 H + Step 1: Hexokinase All of the glycolytic enzymes are found in the cytosol. In glycolysis, glucose is converted into pyruvate. Glucose is a six- memebered ring molecule found in the blood and is usually a result of the breakdown of carbohydrates into sugars. It enters cells through specific transporter proteins that move it from outside the cell into the cell’s cytosol. Glycolysis is the metabolic process that serves as the foundation for both aerobic and anaerobic cellular respiration.
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